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CIPAMI
Clopidogrel to Improve Primary percutaneous coronary intervention in Acute Myocardial Infarction
Ongoing trial
Author(s)
Zeymer U, Arntz H-R, Darius H, Huber K, Senges J
Title(s)
Efficacy and safety of clopidogrel 600 mg administered pre-hospitally to improve primary percutaneous coronary intervention in patients with acute myocardial infarction (CIPAMI): study rationale and design
Reference(s)
Cardiology 2007;108:265–72
Disease
AMI
Purpose
To evaluate the efficacy and safety of clopidogrel in addition to standard ASA and heparin in the pre-hospital setting in patients with AMI scheduled for primary percutaneous coronary intervention
Study design
Randomised, open
Follow-up
7 days or hospital discharge
Patients
Aim 654 patients, aged ≥ 18 years, with acute ST elevation MI < 6 h
Treatment regimen
Clopidogrel, 600 mg loading dose, plus ASA, 500 mg iv, and heparin, 5000 U iv or enoxaparin, 0.5 mg/kg sc, followed by 1 mg/kg bid, or standard ASA and heparin/enoxaparin alone
Results
Not yet available
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