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EXCLAIM
Extended Clinical prophylaxis in Acutely Ill Medical patients
Ongoing trial
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Author(s) |
Hull RD, Schellong SM, Tapson VE, Monreal M, Samama M-M, Turpie AGG, Wildgoose P, Yusen RD |
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Title(s) |
Extended-duration thromboprophylaxis in acutely ill medical patients with recent reduced mobility; methodology for the EXCLAIM study |
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Reference(s) |
J Thromb Thrombolysis 2006;22:31–8 |
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Disease |
Venous thromboembolism |
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Purpose |
To compare the efficacy and safety of extended-duration thromboprophylaxis using enoxaparin with the standard regimen of enoxaparin in acutely ill medical patients with recent reduced mobility |
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Study design |
Randomised, double-blind, placebo-controlled |
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Follow-up |
Aim 6 months |
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Patients |
Aim 4726 acutely ill medical patients, aged ≥ 40 years, with recent reduced mobility |
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Treatment regimen |
Enoxaparin, 40 mg/day sc for 10 ± 4 days, followed by enoxaparin, 40 mg/day, or placebo for 28 ± 4 days |
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Results |
Not yet available |
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