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REGARDS
Reasons for Geographic And Racial Differences in Stroke
Ongoing trial
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Author(s) |
(a) Howard VJ, Cushman M, Pulley L, Gomez CR, Go RC, Prineas RJ, Graham A, Moy CS, Howard G
(b) Howard VJ, McClure LA, Meschia JF, Pulley LV, Orr SC, Friday GH |
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Title(s) |
(a) The Reasons for Geographic And Racial Differences in Stroke Study: objectives and design
(b) High prevalence of stroke symptoms among persons without diagnosis of stroke or transient ischemic attack in a general population |
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Reference(s) |
(a) Neuroepidemiology 2005;25:135–43
(b) Arch Intern Med 2006;166:1952–8 |
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Disease |
Stroke |
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Purpose |
To investigate the causes of geographic and racial differences in incidence of and risk factors for stroke |
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Study design |
Observational |
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Follow-up |
Aim 4 years |
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Patients |
Aim 30,000 individuals, aged ≥ 45 years |
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Results |
In an interim cross-sectional analysis of 18,462 individuals (41% African Americans, 51% women, mean age 65.8 years) who reported no stroke or TIA, the odds of 1 or more symptoms was 1.6 times greater in African American than white participants and 1.2 times greater in women than men. The likelihood of symptoms was not associated with age. The prevalence of 1 or more stroke symptoms was more common among participants in lower socioeconomic status strata, with lower educational level and absence of health insurance |
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Comments |
Data on racial differences in the prevalence of chronic kidney disease among the REGARDS cohort have been published in J Am Soc Nephrol 2006;17:1710–15 |
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