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PAIS
Paracetamol (Acetaminophen) In Stroke
Ongoing trial
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Author(s) |
van Breda EJ, van der Worp HB, van Gemert HMA, Algra A, Kappelle LJ, van Gijn J, Koudstaal PJ, Dippel DWJ, and PAIS investigators |
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Title(s) |
PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480] |
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Reference(s) |
BMC Cardiovasc Disord 2005;5:24 |
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Disease |
Stroke |
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Purpose |
To examine the effects of early antipyretic therapy on the risk of death or dependency in patients with acute stroke |
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Study design |
Randomised, double-blind, placebo-controlled |
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Follow-up |
Aim 3 months |
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Patients |
Aim 2500 patients, aged > 18 years, with acute ischaemic stroke or primary intracerebral haemorrhage and body temperature 36.0–39.0oC |
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Treatment regimen |
Paracetamol, 1000 mg 6 times/day, or placebo for 3 days |
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Results |
Not yet available |
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