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PAIS
Paracetamol (Acetaminophen) In Stroke
Ongoing trial
Author(s)
van Breda EJ, van der Worp HB, van Gemert HMA, Algra A, Kappelle LJ, van Gijn J, Koudstaal PJ, Dippel DWJ, and PAIS investigators
Title(s)
PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480]
Reference(s)
BMC Cardiovasc Disord 2005;5:24
Disease
Stroke
Purpose
To examine the effects of early antipyretic therapy on the risk of death or dependency in patients with acute stroke
Study design
Randomised, double-blind, placebo-controlled
Follow-up
Aim 3 months
Patients
Aim 2500 patients, aged > 18 years, with acute ischaemic stroke or primary intracerebral haemorrhage and body temperature 36.0–39.0oC
Treatment regimen
Paracetamol, 1000 mg 6 times/day, or placebo for 3 days
Results
Not yet available
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