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JATOS
Japanese Trial to assess Optimal Systolic blood pressure in elderly hypertensive patients
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Author(s) |
JATOS Study Group |
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Title(s) |
The Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS): protocol, patient characteristics, and blood pressure during the first 12 months |
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Reference(s) |
Hypertens Res 2005 28:513–20 |
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Disease |
Hypertension |
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Purpose |
To compare the effects of maintaining SBP < 140 mm Hg vs SBP 140–160 mm Hg in elderly patients with hypertension |
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Study design |
Randomised, open |
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Follow-up |
Aim 2 years |
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Patients |
4320 patients (2165 target SBP < 140 mm Hg, 2155 target SBP 140–160 mm Hg), aged 65–85 years, with SBP ≥ 160 mm Hg and DBP < 120 mm Hg |
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Treatment regimen |
Efonidipine, 20–40 mg/day, increased to 60 mg/day or bid if needed to reach target SBP |
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Concomitant therapy |
Other antihypertensive drugs (except calcium antagonists) |
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Results |
Not yet available |
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