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CCS-2
Second Chinese Cardiac Study
Ongoing trial
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Author(s) |
Second Chinese Cardiac Study (CCS-2) Collaborative Group
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Title(s) |
Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction
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Reference(s) |
J Cardiovasc Risk 2000;7:435-41 |
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Disease |
AMI
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Purpose |
To compare the effect of combined clopidogrel and ASA to ASA alone on the risk of major vascular events in patients with suspected AMI
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Study design |
Randomised, placebo-controlled, 2 × 2 factorial
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Follow-up |
Up to 4 weeks
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Patients |
Aim 20,000-40,000 patients admitted to over 1000 Chinese hospitals up to 24 h after the onset of suspected AMI
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Treatment regimen |
After 2-day induction period, ASA, 162 mg once daily, plus clopidogrel, 75 mg once daily, or placebo, plus metoprolol, 5-15 mg iv, then metoprolol CR/XL oral tablets, 200 mg/day, or placebo
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Results |
Not yet available
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