Author(s) |
Hall AS, Murray GD, Ball SG
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Title(s) |
Follow-up study of patients randomly allocated ramipril or placebo for heart failure after myocardial infarction: AIRE Extension (AIREX) study
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Reference(s) |
Lancet 1997;349:1493-7
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Disease |
AMI with heart failure
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Purpose |
To assess the long-term (3 years after the end of AIRE) survival benefits of ramipril compared to placebo in the UK patients from the AIRE study
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Study design |
Retrospective, controlled
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Follow-up |
3 years
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Patients |
603 patients (302 initially on ramipril, 301 initially on placebo)
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Treatment regimen |
See treatment for the AIRE study
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Results |
Death from all causes had occurred in 117/301 previously placebo-treated patients and 83/302 previously ramipril-treated patients. This is a statistically significant relative risk reduction of 36%
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