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EXCELLENT
Efficacy of Xience/promus versus Cypher in reducing Late Loss after stenting
Ongoing trial
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Author(s) |
Park KW, Yoon J-H, Kim J-S, Hahn J-Y, Cho Y-S, Chae I-H, Gwon H-C, Ahn T, Oh B-H, Park J-E, Shim W-H, Shin E-K, Jang Y-S, Kim H-S |
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Title(s) |
Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: Study design and rationale of a Korean multicenter prospective randomized trial |
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Reference(s) |
Am Heart J 2009;157:811–7.e1 |
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Disease |
Coronary artery disease |
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Purpose |
To compare the efficacy and safety of the everolimus-eluting stent vs the sirolimus-eluting stent in the treatment of coronary stenosis and to evaluate the efficacy and safety of 6 vs 12 months of dual antiplatelet therapy |
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Study design |
Randomised, open, 2 x 2 factorial |
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Follow-up |
6, 9 and 12 months |
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Patients |
Aim 1372 patients (1029 everolimus-eluting stent, 343 sirolimus-eluting stent), aged ≥ 18 years, with significant coronary stenosis undergoing PCI |
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Treatment regimen |
Everolimus-eluting stent or sirolimus-eluting stent, and 6- or 12-month clopidogrel therapy |
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Concomitant therapy |
Two substudies of EXCELLENT are planned. The long-term angiographic follow-up substudy will include patients with 9-month and 2-year angiographic follow-up. Another substudy will consider patients undergoing intravascular ultrasound immediately after PCI and after 9 months |
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Results |
Not yet available |
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Comments |
Two substudies of EXCELLENT are planned. The long-term angiographic follow-up substudy will include patients with 9-month and 2-year angiographic follow-up. Another substudy will consider patients undergoing intravascular ultrasound immediately after PCI and after 9 months
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